Charles Hoskinson is CEO and Founder of Input Output Group (IOG, also known as IOHK), the engineering and research company behind the Cardano blockchain. He co-founded Ethereum in late 2013 alongside Vitalik Buterin as one of five original founders, holding the position of chief executive before being removed in 2014 following a dispute over whether the project should operate as a commercial or nonprofit entity. In late 2014, he formed IOHK with former Ethereum colleague Jeremy Wood to build cryptocurrencies and blockchains. Cardano, IOHK's primary project, is a public blockchain and smart contract platform hosting the ADA cryptocurrency. Hoskinson chose not to pursue venture capital for Cardano, citing concerns about blockchain principles and the risk of outsized project control. IOHK has sponsored blockchain research at the University of Edinburgh, Tokyo Institute of Technology, Stanford University, and the University of Wyoming.

Prior to Ethereum, Hoskinson founded the Bitcoin Education Project in 2013, served as founding chairman of the Bitcoin Foundation's education committee, and helped establish the Cryptocurrency Research Group. He also co-founded Invictus Innovations, a Bitcoin-related start-up. In September 2021, he donated $20 million to Carnegie Mellon University's philosophy department to establish the Hoskinson Center for Formal Mathematics. He contributed $1.5 million to fund a 2023 Galileo Project expedition led by Avi Loeb to recover debris from meteorite CNEOS 2014-01-08 near Papua New Guinea. Outside of crypto, he operates an 11,000-acre bison ranch, owns a construction company, and runs an anti-aging healthcare clinic in rural Wyoming. He attended Metropolitan State University of Denver and the University of Colorado Boulder to study mathematics.

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