Rune Christensen is the co-founder and CEO of MakerDAO, the protocol that issues DAI, described as the first stablecoin on the Ethereum blockchain. Since founding MakerDAO in March 2015, he has focused on establishing the organizational structure of the Maker Decentralized Autonomous Organization and the economic foundations of the DAI stablecoin. In August 2024, the Maker protocol rebranded to Sky and launched a new stablecoin, USDS, designed to attract a wider audience by providing access to returns from both decentralised and centralised finance. Sky introduced Sky token rewards for USDS holders and a "stars" system of sub-protocols, with Spark as the first. Christensen has continued to lead governance activity under the Sky brand, publishing a proposal in April 2025 to move the protocol out of its bootstrap funding phase and restructure the Treasury Management Function from a five-step to a four-step revenue waterfall following the completion of Genesis Capital deployments.

Prior to MakerDAO, Christensen co-founded Try China, an international recruiting business focused on placing English teachers from Western countries in China, which he operated from 2011 to 2014. His initial engagement with cryptocurrency began in 2011 with Bitcoin; the collapse of Mt. Gox in 2014 directed his focus toward stablecoins. He also co-founded Raw Power Games, a games development company, in July 2022. Christensen studied International Business at Copenhagen Business School between 2011 and 2013 and Biochemistry at the University of Copenhagen from 2013 to 2014.

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